• Title: Aglow In The Dark: The Revolutionary Science Of Biofluorescence
  • Author: David F. Gruber
  • ISBN: 9780674019218
  • Page: 107
  • Format: Hardcover
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    Aglow In The Dark The Revolutionary Science Of Biofluorescence In the early s in a small shack on the Washington coast ayoung self educated Japanese scientist performed an experiment todetermine what made a certain jellyfish glow The substance hediscovered
    In the early 1960s, in a small shack on the Washington coast, ayoung, self educated Japanese scientist performed an experiment todetermine what made a certain jellyfish glow The substance hediscovered, green fluorescent protein, would revolutionise molecularbiology, transforming our study of everything from the AIDS virus to theworkings of the brain Aglow in the Dark folIn the early 1960s, in a small shack on the Washington coast, ayoung, self educated Japanese scientist performed an experiment todetermine what made a certain jellyfish glow The substance hediscovered, green fluorescent protein, would revolutionise molecularbiology, transforming our study of everything from the AIDS virus to theworkings of the brain Aglow in the Dark follows the path that took thisglowing compound from its inauspicious arrival on the scientific sceneto its present day eminence as one of the most groundbreakingdiscoveries of the 20th Century.

    One Reply to “Aglow In The Dark: The Revolutionary Science Of Biofluorescence”

    1. Fascinating story about the discovery of luminescent and phosphorescent molecules from the sea which are currently used to "illuminate" cellular function.

    2. Excellent book so far. The first half was read in more or less one sitting, it was so interesting and written simply enough for a quick read. The second half is going a bit more slowly because detailed biology starts to bore me after a while, though it's definitely no fault of the author! It's detailed enough to interest those with a background in science, but not so hard that you have to study it. This book focuses heavily on the people involved in the study of biofluorescence, which I enjoy im [...]

    3. This is a wonderful book tracing the history of biofluorescence, with an emphasis on GFP in cell biological research. This is probably the best book I've ever read on florescence, and the interviews with some of the main players in GFP technology are very illuminating. Especially interesting is the contribution Shimomura made to the research, as well as the discovery of red fluorescent variants. A must read for cell biologists interested in the history of the fluorescent proteins they work with. [...]

    4. This is a well-written book, with the science intended for an educated lay audience. I found it factually correct, albeit slightly outdated in this exponentially growing field. My favorite thing about the book is actually how it brings the scientists to the forefront, with their quirks, hobbies, ups and downs, and difficulties along the way (one of the prominent scientists lived in Japan during the nuclear bombings). There were a couple digressions into coral reefs and neuron imaging in the brai [...]

    5. Fun science book. We swam in the glowing sea of dinoflagelates at Vieques and I have been wondering about them ever since. This book explains the science behind the glow and the many modern uses for the glow as well.

    6. A good primer for bioflourescence, told by starting with the first researchers and moving forward. Very readable, seems to be half travelogue, too.

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